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Showing posts with label Thalassemia. Show all posts
Showing posts with label Thalassemia. Show all posts

THALASSEMIA Major ( Cooley's Anemia) -

  • beochemical abnormality affecting either alpha or beta polypeptide chains of globin
  • beta thalassemia refers to inherited hemolytic anemiacharacterized by absence of the beta globulin chain of hemoglobin synthesis
  • very common in middle east
  • this inherited from both parents

SIGNS AND SYMPTOMS:
  • severe chronic hemolytic anemia
  • mark enlargement of the liver and spleen
  • jaundice
THALASSEMIA MINOR (Cooley's trait)-
  • characterized by a defective red cell as seen in laboratory finding


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